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PostPosted: Wed Apr 22, 2020 3:39 am 
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Plook wrote:
A guy my sister went to school with and whom I also knew since I was a we land but only saw him once in the last 30 years (at my moms passing celebration) had a heart attack last Thursday and died, when they tested him he tested positive and had not been feeling well...(this was in Southern California).

The virus sometimes, rarely, attacks the heart, rather than the lungs.

cory1984 wrote:
Anyone else?

We have a friend, whose first cousin once-removed, who had a previous auto-immune condition, died from COVID in Belo Horizonte, MG, Brazil. Her husband also had it and is now cured.

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PostPosted: Wed Apr 22, 2020 7:56 am 
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Mr_Green_Genes wrote:
The virus sometimes, rarely, attacks the heart, rather than the lungs.


I have heard this heart attack thing more than once, I wonder why some people succumb maybe their is an underlying heart condition and the virus is the last straw so to speech...I also so a report about people coming into emergency rooms for some accident or other reason and when they test then the have the virus.


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PostPosted: Sat Apr 25, 2020 5:50 am 
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Stay at home so that we can all see each other healthy, again!


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PostPosted: Mon Apr 27, 2020 10:26 am 
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PostPosted: Wed Apr 29, 2020 11:38 am 
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PostPosted: Wed Apr 29, 2020 11:33 pm 
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On the "glass is half-full and if it isn't pour the glass's contents into a smaller glass" side:

Clean air in Europe during lockdown leads to 11000 fewer deaths:
https://www.theguardian.com/environment ... wer-deaths

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PostPosted: Thu Apr 30, 2020 12:39 pm 
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PostPosted: Thu Apr 30, 2020 3:56 pm 
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PostPosted: Tue May 05, 2020 8:12 am 
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India To Launch World's Largest Evacuation On Thursday: 10-Point Guide
Flights from India will go to US, the Philippines, Singapore, Bangladesh, UAE, UK, Saudi Arabia, Qatar, Singapore, Phillippines, Oman, Bahrain and Kuwait.

All IndiaReported by Vishnu Som, Edited by Deepshikha GhoshUpdated: May 05, 2020 08:07 pm IST
https://www.ndtv.com/india-news/coronavirus-india-lockdown-14-800-stranded-indians-on-64-flights-indias-massive-evacuation-plan-2223510

New Delhi: Hundreds of thousands of Indians stranded abroad because of the coronavirus crisis will be brought back by air and by sea from Thursday in the world's largest evacuation mission. More than 3 lakh Indians have requested a flight home. Those taking the special flights will be charged around Rs 50,000 from Europe and Rs 1 lakh from the US. Naval warships will also set out for Indians stuck in West Asia and the Maldives. This is the biggest exercise since national airline Air India flew back 1,70,000 during the first Gulf War.
Here are 10 developments in this big story:

1 Over 14,800 Indians in 13 countries will be brought back by 64 flights in the first week, says the foreign ministry. "We will be bringing back only Indian citizens, no OCI (Overseas Citizen of India) card holders," say sources.

2 On the first day of evacuation on May 7, 10 flights will bring back 2,300 Indians stranded because of airspace closures by various countries to slow the spread of coronavirus.

3 Over the next few days, the government will operate 10 flights to the UAE, seven each to the US and UK, five flights to Saudi Arabia, five flights to Singapore and two flights to Qatar. There will also be flights to Malaysia, Bangladesh, five flights each to Kuwait and Philippines and two flights each to Oman and Bahrain.

4 Each flight will have between 200 and 300 passengers to ensure social distancing. Before boarding the special flights, the passengers need to declare whether they have fever, cough, diabetes or any respiratory disease.

5 Indians with valid visas will be allowed to fly out on the same special flights bringing citizens back, provided they are permitted into their destination country.

6 All passengers will be screened and only asymptomatic passengers would be allowed to travel, the government says. On arrival, they will be quarantined for 14 days, says the home ministry.

7 The three ships deployed by the Navy are INS Shardul, INS Magar and INS Jalashwa. The INS Jalashwa, based in Visakhapatnam, has steamed into the Arabian Sea for the mission. The Indian Air Force has prepared about 30 aircraft, including Boeing Co.'s C-17 Globemaster and Lockheed Martin Corp.'s C-130J Super Hercules, for the mission.

8 India banned all flights in late March as it imposed one of the world's strictest lockdowns to check COVID-19, leaving thousands of workers and students stranded. Till now, the government had resisted evacuations, given the logistical and safety nightmare of bringing back and quarantining returning citizens.

9 Priority will be given to pregnant women, the elderly, people with medical emergencies and ones with bereavement or serious illness in their immediate family, apart from migrant workers who have been laid off, say officials.

10 India has more than 46,000 coronavirus cases; almost 1,600 have died.

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PostPosted: Wed May 06, 2020 2:15 am 
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PostPosted: Sat May 09, 2020 5:04 am 
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Bol$onaro is having a barbecue for 30, or maybe 3,000, so he says, in the official President Palace, now.

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PostPosted: Mon May 11, 2020 1:46 am 
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^^That was only autofake-news. He went jet-skying instead, while we reached the 10,000 dead Brazilians from COVID-19 (some projections say that is 4 X smaller that the actual number, due to sub-notification)...

But not everything is lost:

Cannabis shows promise blocking coronavirus infection: Alberta researcher

Author of the article: Bill Kaufmann

Publishing date: 4 days ago • 2 minute read

Cannabis extracts are showing potential in making people more resistant to the novel coronavirus, says an Alberta researcher leading a study.

After sifting through 400 cannabis strains, researchers at the University of Lethbridge are concentrating on about a dozen that show promising results in ensuring less fertile ground for the potentially lethal virus to take root, said biological scientist Dr. Igor Kovalchuk.

“A number of them have reduced the number of these (virus) receptors by 73 per cent, the chance of it getting in is much lower,” said Kovalchuk.

“If they can reduce the number of receptors, there’s much less chance of getting infected.”

Employing cannabis sativa strains over the past three months, the researcher said the effective balance between cannabis components THC and CBD — the latter more typically associated with medical use — is still unclear in blocking the novel coronavirus.

“It will take a long time to find what the active ingredient is — there may be many,” said Kovalchuk, whose Pathway *SPAM* is owned partly by Olds-based licensed cannabis producer Sundial Growers and partnered with Alberta cannabis researcher Swysh.

But it’s generally the anti-inflammatory properties of high-CBD content that have shown most promise, he added.

“We focus more on the higher CBD because people can take higher doses and not be impaired,” said Kovalchuk.

The study under Health Canada licence using artificial human 3-D tissue models has been seeking ways to hinder the highly contagious novel coronavirus from finding a host in the lungs, intestines, and oral cavity.

If successful, the work could find practical medical use in the form of mouth wash, gargle, inhalants or gel caps, said Kovalchuk.

“It would be cheaper for people and have a lot less side-effects,” he said.

But the absence of clinical trials remains a barrier, and funding from an increasingly cash-strapped cannabis industry isn’t there to fuel that, said Kovalchuk.

“We have clinicians who are willing to work with us but for a lot of companies in the cannabis business, it’s significant cash that they can’t afford,” he said.

The scientist emphasized the findings wouldn’t lead to a vaccine — something “less specific and precise” but nonetheless another possible weapon against COVID-19.

“The extracts of our most successful and novel high CBD C sativa lines, pending further investigation, may become a useful and safe addition to the treatment of COVID-19 as an adjunct therapy,” said Kovalchuk.

“Given the current dire and rapidly evolving epidemiological situation, every possible therapeutic opportunity and avenue must be considered.”

Israeli researchers have begun clinical trials of CBD as a treatment to repair cells damaged by COVID-19 by using its anti-inflammatory abilities.

It’s thought CBD could enhance the traditional effect of steroids in such treatment of patients in life-threatening condition and also bolster the immune system.

It’s the kind of research and his own that deserves government support in Canada, whose federal government has pledged $1.1 billion in funding for COVID-19 research said the U of L scientist.

“Our work could have a huge influence — there aren’t many drugs that have the potential of reducing infection by 70 to 80 per cent,” he said.

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University of Lethbridge researcher Igor Kovalchuk is leading a study on medical cannabis as a potential therapy for COVID-19.

BKaufmann@postmedia.com

Twitter: @BillKaufmannjrn

https://calgaryherald.com/cannabis/cannabis-shows-promise-blocking-coronavirus-infection-alberta-researcher/

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PostPosted: Mon May 11, 2020 3:07 am 
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NZ will be voting on both cannabis legalization and euthanasia this coming September.....
baby steps towards a pain-free world..... 8)

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PostPosted: Wed May 13, 2020 9:57 pm 
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PostPosted: Sat May 16, 2020 3:01 am 
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PBS Nova just came out with a high-science Covid-19 show on things like: different ways to make a vaccine, treatments, hopefully more than one of them will work, and in lieu of those, then 18 months until 70% of us get it which should get us to herd immunity (after a million deaths), and contact tracing as the way to reopen...etc...

Here's a link, the science stuff begins 20 minutes in...

https://www.pbs.org/wgbh/nova/video/decoding-covid-19/

Does not play in Internet Explorer (lol), but plays fine in Chrome and Firefox.

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PostPosted: Sat May 16, 2020 6:12 am 
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^^^Thanks!

A scientifically accurate model of the SARS-CoV-2 virus

Authors of the most detailed models of the Ebola, HIV, and Flu viruses created the 3D model of SARS-CoV-2 coronavirus at atomic resolution


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The biomedical visualization studio Visual Science has created the most detailed and scientifically accurate 3D model of the full SARS-CoV-2 virus at atomic resolution. The model is based on the latest scientific research into the structure of coronaviruses and communication with virologists currently working with the virus. Molecular and computational biologists from Visual Science with help and advice from leading specialists in structural virology of coronaviruses built the most accurate model of the SARS-CoV-2 viral particle currently available.

The SARS-CoV-2 virus model is a part of Visual Science's non-commercial Viral Park project. Its past successes include models of HIV, influenza A/H1N1, Ebola, papilloma, and Zika virions. HIV virion model has been awarded first place at the 2010 Science and Engineering Visualization Challenge (SEVC), a competition organized by Science magazine and the National Science Foundation. A year later, the 3D model of the Ebola virus received an Honorable Mention at The Vizzies 2011, an award also organized by Science magazine and the National Science Foundation (NSF).

"Visual Science employed the same techniques of structural bioinformatics used in basic research and drug development. The model reflects scientists' current understanding of the virus's architecture. It includes surface protein spikes that interact with the receptors on the surface of the human cell to get inside, lipid envelope with an integrated layer of matrix proteins, and a genome assembly, reconstructed based on the available scientific data", says Ivan Konstantinov, CEO, and founder of Visual Science.

"We use published scientific information about the virus and structures of the viral components available in the Protein Data Bank as a starting point. After thorough and careful analysis of the data, we reconstruct complete models of the viral proteins and their interactions using computational biology software and then assemble the whole model of the virion based on these structures and information about the virion composition and assembly", says Yury Stefanov, Ph.D., scientific director of the Visual Science.

The SARS-CoV-2 virus model was created by scientists and CGI specialists at Visual Science, a world leader in scientific visualization that specializes in micro- and nanoscopic objects and processes. Virologists from leading laboratories working with structural biology of coronaviruses provided valuable feedback and consultations that helped to make the model scientifically accurate.

"In their usual stunning style, the talented illustrators at Visual Science have created a model of the SARS-CoV-2 virus particle. It shows, in great detail, the intact particle with its spike glycoproteins embedded in the membrane. A cutaway view reveals the viral nucleocapsid inside the particle. These gorgeous images will enhance our understanding of the virus particle, and for the non-scientist will make even more palpable the virus that is infecting millions of people", says Vincent Racaniello, Ph.D., Higgins Professor at the Department of Microbiology & Immunology of Columbia University, New York.

"Great work on the spike and the images! Really well done. The spikes are about as accurate as they can be given our current knowledge. The images are striking", comments Dr. Jason S. McLellan, Associate Professor at the Molecular Biosciences Department of the University of Texas at Austin.

"Wow, that s really neat I love the model where it is open and you can see the RNP new favorite SARS-CoV 2 model", says Dr. Benjamin Neuman, Professor, and Chair of Biological Sciences of Texas A&M University-Texarkana.

###

Additional info about the Visual Science

Models and visualizations created as part of the Viral Park project have received prizes from Science magazine and the National Science Foundation. They have appeared in leading media outlets such as Science, Nature Medicine, The New York Times, The Washington Post, Scientific American, Wired UK, Spiegel, Stern, National Geographic, GEO, and others.

Illustrations of the models have also been included in the authoritative textbook Vaccines by Stanley Plotkin and in Cell journal's Picture Show, which coincided with the 30th anniversary of the discovery of HIV.

The goal of the Viral Park project is to popularize scientific exploration of the microworld through visualization and the opportunity to see the world's most widespread and lethal human viruses at the atomic level.

Françoise Barré-Sinoussi, who received a Nobel Prize in 2008 for her work on the discovery of HIV, has used Visual Science's model of this virus in presentations.

Follow Visual Science on:

Instagram: https://www.instagram.com/visualscience/
Twitter: https://twitter.com/visualscience
Facebook: https://www.facebook.com/VisualScience/

https://www.eurekalert.org/pub_releases/2020-05/vs-asa051320.php

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PostPosted: Sat May 16, 2020 10:52 am 
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^^Bruce Bickford could have had fun with that design and some clay!^^

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PostPosted: Sat May 16, 2020 2:33 pm 
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Why does it look like someone has made it on a knitting Nancy :shock:


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PostPosted: Mon May 18, 2020 3:10 am 
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Epidemic, Endemic, and Eradication Simulations (12:50)
https://www.youtube.com/watch?v=7OLpKqTriio

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PostPosted: Mon May 18, 2020 8:12 am 
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PostPosted: Sat May 23, 2020 6:22 am 
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Coronavirus Does Not Spread Easily on Surfaces, C.D.C. Says

https://www.nytimes.com/2020/05/22/health/cdc-coronavirus-touching-surfaces.html

If you’re worried about wiping down grocery bags or disinfecting mailed packages, this C.D.C. guidance might bring some relief. It’s not new information; the agency has been saying this for months.

By Jacey Fortin

Published May 22, 2020
Updated May 23, 2020, 12:05 a.m. ET

Guidelines from the Centers for Disease Control and Prevention making the rounds this week on the internet are clarifying what we know about the transmission of the coronavirus.

The virus does not spread easily via contaminated surfaces, according to the C.D.C. For those who were worried about wiping down grocery bags or disinfecting mailed packages, the news headlines highlighting this guidance in recent days might have brought some relief.

But this information is not new: The C.D.C. has been using similar language for months. If anything, the headlines have pulled into sharper focus what we already know about the virus.

The coronavirus is thought to spread mainly from one person to another, typically through droplets when an infected person sneezes, coughs or talks at close range — even if that person is not showing symptoms.

“The virus that causes Covid-19 is spreading very easily and sustainably between people,” the C.D.C. says on its website. “Information from the ongoing Covid-19 pandemic suggest that this virus is spreading more efficiently than influenza, but not as efficiently as measles, which is highly contagious.”

The website also says that people can become infected by “touching a surface or object that has the virus on it and then touching their own mouth, nose, or possibly their eyes.” But those are “not thought to be the main way the virus spreads.”

According to cached versions of the website that are available online, this language has remained largely unchanged since at least late March.

The format of the C.D.C. website was slightly altered this month, but the language about surfaces remained the same. It appears to have been placed under a new subheading — “The virus does not spread easily in other ways” — on May 11, and more information about the difficulty of catching the virus from animals was added.

Kristen Nordlund, a spokeswoman for the agency, told The Washington Post that the revisions followed an internal review and were the product of “usability testing.”

“Our transmission language has not changed,” Ms. Nordlund said. “Covid-19 spreads mainly through close contact from person to person.”

Experts at the C.D.C. and elsewhere are still learning about the new coronavirus.

There are questions about how the density of virus particles could affect transmission rates. Researchers don’t yet know whether all speech, cough and sneeze droplets carrying the particles are equally infectious, or if a specific amount of virus needs to be transmitted for a person to get sick by breathing it in. A study last week found that talking alone can launch thousands of droplets into the air, and that they can remain suspended for eight to 14 minutes.

It seems that the virus spreads most easily when people are in close contact with one another — in a conversation, for example — or gathered in poorly ventilated spaces, said Linsey Marr, an aerosol scientist at Virginia Tech.

She said that in order for a person to catch the virus from a surface, it would seem that a few things would have to happen. First, the virus would have to be transmitted to the surface in large enough amounts. Then, it would have to survive on that surface until it was touched by someone else. And even if it was eventually transferred to, say, a person’s finger, it would then have to survive on the skin until that person happened to touch an eye or mouth.

“There’s just a lot more conditions that have to be met for transmission to happen via touching these objects,” Dr. Marr said.

A lot of what we know about how long the virus lives on surfaces comes from a study published in The New England Journal of Medicine in March. The study found that the virus can survive, under ideal conditions, up to three days on hard metal surfaces and plastic and up to 24 hours on cardboard.

And since catching the coronavirus from a contaminated surface is still considered a possibility, people who prefer to wipe down bags, boxes or park benches can still do so. The C.D.C. recommends washing your hands often and regularly cleaning or disinfecting frequently touched surfaces.
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PostPosted: Sat May 23, 2020 6:40 am 
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^^^That's good to read!

Amigos, I take the liberty of inviting ALL OF YOU in helping the efforts to yield computational power to protein structure analyses for many diseases, including COVID.

You have to install the program for folding@home and you can choose to set it for working only when your computer is idle.

You can join the Zappateers team, in the name of Zappa, as I don't speak for the team, but I've noticed frustration that so few have stepped forward.

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My guitar wants to kill SARS-Cov-2 and I want you to fight COVID in the name of Zappa!

Ob wrote:
Join the Zappateers Team (number 263939).


The effort was mentioned in the very much recommended running chart-article linked below and was started by Ob at Zappateers:

http://www.zappateers.com/bb/viewtopic.php?t=33671


ccu cgg cgg gca

The 12 letters that changed the world

The genome of the new coronavirus harbors a short sequence suspected of being the main culprit of its uniquely infectious and aggressive nature


https://elpais.com/elpais/2020/05/18/ciencia/1589818040_544543.html

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PostPosted: Tue May 26, 2020 3:35 am 
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PostPosted: Tue May 26, 2020 9:30 am 
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PostPosted: Tue May 26, 2020 11:36 am 
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